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A CD146 FACS Protocol Enriches for Luminal Keratin 14/19 Double Positive Human Breast Progenitors

Human breast cancer is believed to arise in luminal progenitors within the normal breast. A subset of these are double positive (DP) for basal and luminal keratins and localizes to a putative stem cell zone within ducts. We here present a new protocol based on a combination of CD146 with CD117 and C...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gerdur Ísberg, Ólöf, Kim, Jiyoung, Fridriksdottir, Agla J., Morsing, Mikkel, Timmermans-Wielenga, Vera, Rønnov-Jessen, Lone, Petersen, Ole W., Villadsen, René
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795797/
https://ncbi.nlm.nih.gov/pubmed/31619692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50903-9
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