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Ionizing radiation induces ATM dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cells

Human embryonic stem (ES) cells are highly sensitive to environmental insults including DNA damaging agents, responding with high levels of apoptosis. In order to understand the response of human ES cells to DNA damage, we investigated the function of the ataxia telangiectasia mutated (ATM) DNA dama...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Momčilović, Olga, Choi, Serah, Varum, Sandra, Bakkenist, Christopher, Schatten, Gerald, Navara, Christopher
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340923/
https://ncbi.nlm.nih.gov/pubmed/19544417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.123
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