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Brd4 Shields Chromatin from ATM Kinase Signaling Storms
Upon activation, ataxia telangiectasia mutated (ATM) kinase rapidly phosphorylates hundreds of proteins, setting off chaotic signaling storms from areas of damaged chromatin. Recent work by Kaidi and Jackson and Floyd et al. advance our knowledge of the mechanisms that initiate or limit ATM kinase s...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3936316/ https://ncbi.nlm.nih.gov/pubmed/24045152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004622 |
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