Ellipticine increases the superhelical density of intracellular SV40 DNA by intercalation.

We investigated the in vivo effect of ellipticine, a mammalian topoisomeraseII(topoII) inhibitor, on SV40 DNA topology. In contrast to epipodophyllotoxins, ellipticine did not cause significant double stranded cleavage of intracellular SV40 DNA. Furthermore, ellipticine reduced cleavage induced by e...

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Bibliografische gegevens

Gepubliceerd in:	Nucleic Acids Res
Hoofdauteurs:	Chu, Y, Hsu, M T
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Oxford University Press 1992
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334084/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1324474/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.15.4033
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