Ellipticine increases the superhelical density of intracellular SV40 DNA by intercalation.
We investigated the in vivo effect of ellipticine, a mammalian topoisomeraseII(topoII) inhibitor, on SV40 DNA topology. In contrast to epipodophyllotoxins, ellipticine did not cause significant double stranded cleavage of intracellular SV40 DNA. Furthermore, ellipticine reduced cleavage induced by e...
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| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
1992
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| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334084/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1324474/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.15.4033 |
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