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Ellipticine increases the superhelical density of intracellular SV40 DNA by intercalation.
We investigated the in vivo effect of ellipticine, a mammalian topoisomeraseII(topoII) inhibitor, on SV40 DNA topology. In contrast to epipodophyllotoxins, ellipticine did not cause significant double stranded cleavage of intracellular SV40 DNA. Furthermore, ellipticine reduced cleavage induced by e...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
1992
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC334084/ https://ncbi.nlm.nih.gov/pubmed/1324474 |
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