Interleukin-1β and transforming growth factor-β cooperate to induce neurosphere formation and increase tumorigenicity of adherent LN-229 glioma cells

INTRODUCTION: Glioma stem cells (GSCs) have the property of self-renewal and appear to be a driving force for the initiation and recurrence of gliomas. We recently found that the human tumorigenic LN-229 glioma cell line failed to form neurospheres in serum-free conditions and generated mostly small...

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Detalhes bibliográficos
Main Authors: Wang, Lei, Liu, Ziyan, Balivada, Sivasai, Shrestha, Tej, Bossmann, Stefan, Pyle, Marla, Pappan, Loretta, Shi, Jishu, Troyer, Deryl
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340549/
https://ncbi.nlm.nih.gov/pubmed/22330721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt96
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