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Heparin Modulates the Conformation and Signaling of Platelet Integrin αIIbβ3
INTRODUCTION: The glycosaminoglycan heparin has been shown to bind to platelet integrin αIIbβ3 and induce platelet activation and aggregation, although the relationship between binding and activation is unclear. We analyzed the interaction of heparin and αIIbβ3 in detail, to obtain a better understa...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340540/ https://ncbi.nlm.nih.gov/pubmed/22197178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2011.11.054 |
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