Somatostatin receptor subtype-4 agonist NNC 26-9100 decreases extracellular and intracellular Aβ(1-42) trimers

Soluble amyloid β-protein (Aβ) oligomers are primary mediators of synaptic dysfunction associated with the progression of Alzheimer’s disease. Such Aβ oligomers exist dependent on their rates of aggregation and metabolism. Use of selective somatostatin receptor-subtype agonists have been identified...

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Bibliografiska uppgifter
Huvudupphovsmän: Sandoval, Karin E., Farr, Susan A., Banks, William A., Crider, Albert M., Morley, John E., Witt, Ken A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340534/
https://ncbi.nlm.nih.gov/pubmed/22449380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.03.020
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