Loss of Sialic Acid Binding Domain Redirects Protein σ1 to Enhance M Cell-Directed Vaccination

Ovalbumin (OVA) genetically fused to protein sigma 1 (pσ1) results in tolerance to both OVA and pσ1. Pσ1 binds in a multi-step fashion, involving both protein- and carbohydrate-based receptors. To assess the relative pσ1 components responsible for inducing tolerance and the importance of its sialic...

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Bibliographic Details
Main Authors: Zlotkowska, Dagmara, Maddaloni, Massimo, Riccardi, Carol, Walters, Nancy, Holderness, Kathryn, Callis, Gayle, Rynda-Apple, Agnieszka, Pascual, David W.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340367/
https://ncbi.nlm.nih.gov/pubmed/22558374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036182
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