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Oral Escherichia coli Colonization Factor Antigen I (CFA/I) Fimbriae Ameliorate Arthritis via IL-35, not IL-27
A Salmonella therapeutic expressing enterotoxigenic E. coli colonization factor antigen I (CFA/I) fimbriae protects against collagen-induced arthritis (CIA) by eliciting two regulatory T cell (Treg) subsets: TGF-β-producing Foxp3(−)CD39(+)CD4(+) and IL-10-producing Foxp3(+)CD39(+)CD4(+) T cells. How...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3903302/ https://ncbi.nlm.nih.gov/pubmed/24337375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302018 |
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