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Stereocontrol in a Combined Allylic Azide Rearrangement and Intramolecular Schmidt Reaction

Preequilibration of an interconverting set of isomeric allylic azides is coupled with an intramolecular Schmidt reaction to stereoselectively afford substituted lactams. The effect of substitution and a preliminary mechanistic study are reported. The synthetic potential of this method is demonstrate...

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Detalhes bibliográficos
Main Authors: Liu, Ruzhang, Gutierrez, Osvaldo, Tantillo, Dean J., Aube, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340293/
https://ncbi.nlm.nih.gov/pubmed/22490078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja300369c
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