Meiotic Competent Human Germ Cell-like Cells Derived from Human Embryonic Stem Cells Induced by BMP4/WNT3A Signaling and OCT4/EpCAM (Epithelial Cell Adhesion Molecule) Selection

The establishment of an effective germ cell selection/enrichment platform from in vitro differentiating human embryonic stem cells (hESCs) is crucial for studying the molecular and signaling processes governing human germ cell specification and development. In this study, we developed a germ cell-en...

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Detalhes bibliográficos
Main Authors: Chuang, Ching-Yu, Lin, Kuo-I, Hsiao, Michael, Stone, Lee, Chen, Hsin-Fu, Huang, Yen-Hua, Lin, Shau-Ping, Ho, Hong-Nerng, Kuo, Hung-Chih
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340282/
https://ncbi.nlm.nih.gov/pubmed/22396540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.338434
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