MiR-3120 Is a Mirror MicroRNA That Targets Heat Shock Cognate Protein 70 and Auxilin Messenger RNAs and Regulates Clathrin Vesicle Uncoating

We show that a single gene locus gives rise to two fully processed and functional miRNAs, i.e. that due to imperfect base pairing, two distinct microRNAs (miRNAs) can be produced from the fully complementary DNA strands. The antisense strand encodes miR-214, which is transcribed by its own promoter,...

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Autors principals: Scott, Helen, Howarth, Joanna, Lee, Youn Bok, Wong, Liang-Fong, Bantounas, Ioannis, Phylactou, Leonidas, Verkade, Paul, Uney, James. B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
RNA
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340243/
https://ncbi.nlm.nih.gov/pubmed/22393045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.326041
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