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Endocytosis and clathrin-uncoating defects at synapses of auxilin knockout mice

Neuronally expressed auxilin and ubiquitously expressed cyclin-G-dependent kinase (GAK) are homologous proteins that act as cochaperones to support the Hsc70-dependent clathrin uncoating of clathrin-coated vesicles. GAK was previously shown to be essential in mouse during embryonic development and i...

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Detalhes bibliográficos
Main Authors: Yim, Yang-In, Sun, Tao, Wu, Ling-Gang, Raimondi, Andrea, De Camilli, Pietro, Eisenberg, Evan, Greene, Lois E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840126/
https://ncbi.nlm.nih.gov/pubmed/20160091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000738107
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