A Helical Conotoxin from Conus imperialis Has a Novel Cysteine Framework and Defines a New Superfamily

Cone snail venoms are a rich source of peptides, many of which are potent and selective modulators of ion channels and receptors. Here we report the isolation and characterization of two novel conotoxins from the venom of Conus imperialis. These two toxins contain a novel cysteine framework, C-C-C-C...

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Détails bibliographiques
Auteurs principaux: Ye, Mingyu, Khoo, Keith K., Xu, Shaoqiong, Zhou, Mi, Boonyalai, Nonlawat, Perugini, Matthew A., Shao, Xiaoxia, Chi, Chengwu, Galea, Charles A., Wang, Chunguang, Norton, Raymond S.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
Sujets:
Protein Structure and Folding
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340241/
https://ncbi.nlm.nih.gov/pubmed/22399292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334615
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