A Helical Conotoxin from Conus imperialis Has a Novel Cysteine Framework and Defines a New Superfamily

Cone snail venoms are a rich source of peptides, many of which are potent and selective modulators of ion channels and receptors. Here we report the isolation and characterization of two novel conotoxins from the venom of Conus imperialis. These two toxins contain a novel cysteine framework, C-C-C-C...

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Detalhes bibliográficos
Main Authors: Ye, Mingyu, Khoo, Keith K., Xu, Shaoqiong, Zhou, Mi, Boonyalai, Nonlawat, Perugini, Matthew A., Shao, Xiaoxia, Chi, Chengwu, Galea, Charles A., Wang, Chunguang, Norton, Raymond S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340241/
https://ncbi.nlm.nih.gov/pubmed/22399292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334615
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