A Helical Conotoxin from Conus imperialis Has a Novel Cysteine Framework and Defines a New Superfamily

Cone snail venoms are a rich source of peptides, many of which are potent and selective modulators of ion channels and receptors. Here we report the isolation and characterization of two novel conotoxins from the venom of Conus imperialis. These two toxins contain a novel cysteine framework, C-C-C-C...

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Bibliografiske detaljer
Main Authors: Ye, Mingyu, Khoo, Keith K., Xu, Shaoqiong, Zhou, Mi, Boonyalai, Nonlawat, Perugini, Matthew A., Shao, Xiaoxia, Chi, Chengwu, Galea, Charles A., Wang, Chunguang, Norton, Raymond S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340241/
https://ncbi.nlm.nih.gov/pubmed/22399292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334615
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