Disabled-2 Protein Facilitates Assembly Polypeptide-2-independent Recruitment of Cystic Fibrosis Transmembrane Conductance Regulator to Endocytic Vesicles in Polarized Human Airway Epithelial Cells

Cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-activated Cl(−) channel expressed in the apical plasma membrane of fluid-transporting epithelia, where the plasma membrane abundance of CFTR is in part controlled by clathrin-mediated endocytosis. The protein networks that control...

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Bibliographic Details
Main Authors: Cihil, Kristine M., Ellinger, Philipp, Fellows, Abigail, Stolz, Donna Beer, Madden, Dean R., Swiatecka-Urban, Agnieszka
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340218/
https://ncbi.nlm.nih.gov/pubmed/22399289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.341875
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