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Tissue-specific control of CFTR endocytosis by Dab2: Cargo recruitment as a therapeutic target
Clathrin-mediated endocytosis dynamically regulates cell membrane abundance of CFTR and plays an essential role in CFTR-dependent Cl(-) conductance in fluid-transporting epithelia. It requires two closely related, but distinct processes: assembly of the clathrin coat and recruitment of cargo protein...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Landes Bioscience
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3502210/ https://ncbi.nlm.nih.gov/pubmed/23181163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.21375 |
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