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Tissue-specific control of CFTR endocytosis by Dab2: Cargo recruitment as a therapeutic target

Clathrin-mediated endocytosis dynamically regulates cell membrane abundance of CFTR and plays an essential role in CFTR-dependent Cl(-) conductance in fluid-transporting epithelia. It requires two closely related, but distinct processes: assembly of the clathrin coat and recruitment of cargo protein...

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Hlavní autoři: Madden, Dean R., Swiatecka-Urban, Agnieszka
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502210/
https://ncbi.nlm.nih.gov/pubmed/23181163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.21375
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