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Akt recruits Dab2 to albumin endocytosis in the proximal tubule
Proximal tubule epithelial cells have a highly sophisticated endocytic machinery to retrieve the albumin in the glomerular filtrate. The megalin-cubilin complex and the endocytic adaptor disabled-2 (Dab2) play a pivotal role in albumin endocytosis. We previously demonstrated that protein kinase B (A...
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| Publicado no: | Am J Physiol Renal Physiol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4269696/ https://ncbi.nlm.nih.gov/pubmed/25253241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00454.2014 |
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