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c-Cbl Facilitates Endocytosis and Lysosomal Degradation of Cystic Fibrosis Transmembrane Conductance Regulator in Human Airway Epithelial Cells
Cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-activated Cl(−) channel expressed in the apical membrane of fluid-transporting epithelia. The apical membrane density of CFTR channels is determined, in part, by endocytosis and the postendocytic sorting of CFTR for lysosomal degra...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930700/ https://ncbi.nlm.nih.gov/pubmed/20525683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.139881 |
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