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Structural Characterization of Streptococcus pneumoniae Serotype 9A Capsule Polysaccharide Reveals Role of Glycosyl 6-O-Acetyltransferase wcjE in Serotype 9V Capsule Biosynthesis and Immunogenicity
The putative capsule O-acetyltransferase gene wcjE is highly conserved across various Streptococcus pneumoniae serotypes, but the role of the gene in capsule biosynthesis and bacterial fitness remains largely unclear. Isolates expressing pneumococcal serotype 9A arise from precursors expressing wcjE...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340191/ https://ncbi.nlm.nih.gov/pubmed/22367197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.346924 |
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