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Structural Characterization of Streptococcus pneumoniae Serotype 9A Capsule Polysaccharide Reveals Role of Glycosyl 6-O-Acetyltransferase wcjE in Serotype 9V Capsule Biosynthesis and Immunogenicity

The putative capsule O-acetyltransferase gene wcjE is highly conserved across various Streptococcus pneumoniae serotypes, but the role of the gene in capsule biosynthesis and bacterial fitness remains largely unclear. Isolates expressing pneumococcal serotype 9A arise from precursors expressing wcjE...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Calix, Juan J., Saad, Jamil S., Brady, Allison M., Nahm, Moon H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340191/
https://ncbi.nlm.nih.gov/pubmed/22367197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.346924
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