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Analysis of Binding Sites on Complement Factor I Using Artificial N-Linked Glycosylation
Factor I (FI) is a serine protease that inhibits all complement pathways by degrading activated complement components C3b and C4b. FI functions only in the presence of several cofactors, such as factor H, C4b-binding protein, complement receptor 1, and membrane cofactor protein. FI is composed of tw...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340171/ https://ncbi.nlm.nih.gov/pubmed/22393059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.326298 |
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