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Y265C DNA polymerase beta knockin mice survive past birth and accumulate base excision repair intermediate substrates
DNA is susceptible to damage by a wide variety of chemical agents that are generated either as byproducts of cellular metabolism or exposure to man-made and harmful environments. Therefore, to maintain genomic integrity, having reliable DNA repair systems is important. DNA polymerase β is known to b...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340078/ https://ncbi.nlm.nih.gov/pubmed/22493258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200800109 |
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