Dual functions of the Hsm3 protein in chaperoning and scaffolding regulatory particle subunits during the proteasome assembly

The 26S proteasome, a molecular machine responsible for regulated protein degradation, consists of a proteolytic core particle (20S CP) associated with 19S regulatory particles (19S RPs) subdivided into base and lid subcomplexes. The assembly of 19S RP base subcomplex is mediated by multiple dedicat...

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Bibliographische Detailangaben
Hauptverfasser: Barrault, Marie-Bénédicte, Richet, Nicolas, Godard, Chloe, Murciano, Brice, Le Tallec, Benoît, Rousseau, Erwann, Legrand, Pierre, Charbonnier, Jean-Baptiste, Le Du, Marie-Hélène, Guérois, Raphaël, Ochsenbein, Françoise, Peyroche, Anne
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340050/
https://ncbi.nlm.nih.gov/pubmed/22460800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116538109
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