Cargando...

Misfolding of Proteins with a Polyglutamine Expansion Is Facilitated by Proteasomal Chaperones

Deposition of misfolded proteins with a polyglutamine expansion is a hallmark of Huntington disease and other neurodegenerative disorders. Impairment of the proteolytic function of the proteasome has been reported to be both a cause and a consequence of polyglutamine accumulation. Here we found that...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Rousseau, Erwann, Kojima, Rieko, Hoffner, Guylaine, Djian, Philippe, Bertolotti, Anne
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615503/
https://ncbi.nlm.nih.gov/pubmed/18986984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806256200
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!