Peptidyl-prolyl Isomerase Pin1 Controls Down-regulation of Conventional Protein Kinase C Isozymes

The down-regulation or cellular depletion of protein kinase C (PKC) attendant to prolonged activation by phorbol esters is a widely described property of this key family of signaling enzymes. However, neither the mechanism of down-regulation nor whether this mechanism occurs following stimulation by...

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Bibliografske podrobnosti
Main Authors: Abrahamsen, Hilde, O'Neill, Audrey K., Kannan, Natarajan, Kruse, Nicole, Taylor, Susan S., Jennings, Patricia A., Newton, Alexandra C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339987/
https://ncbi.nlm.nih.gov/pubmed/22318721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.349753
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