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Sphingosine 1-Phosphate (S1P) Regulates Glucose-stimulated Insulin Secretion in Pancreatic Beta Cells

Recent studies suggest that sphingolipid metabolism is altered during type 2 diabetes. Increased levels of the sphingolipid ceramide are associated with insulin resistance. However, a role for sphingolipids in pancreatic beta cell function, or insulin production, and release remains to be establishe...

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Autori principali: Cantrell Stanford, Jamie, Morris, Andrew J., Sunkara, Manjula, Popa, Gabriel J., Larson, Kara L., Özcan, Sabire
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339968/
https://ncbi.nlm.nih.gov/pubmed/22389505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.268185
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