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Granule-Mediated Release of Sphingosine-1-Phosphate by Activated Platelets*

Sphingosine-1-phosphate (S1P) is an intracellularly generated bioactive lipid essential for development, vascular integrity, and immunity. These functions are mediated by S1P-selective cell surface G-protein coupled receptors. S1P signaling therefore requires extracellular release of this lipid. Sev...

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Dettagli Bibliografici
Pubblicato in:Biochim Biophys Acta
Autori principali: Jonnalagadda, Deepa, Sunkara, Manjula, Morris, Andrew J., Whiteheart, Sidney W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223867/
https://ncbi.nlm.nih.gov/pubmed/25158625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2014.08.013
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