The transporter Spns2 is required for secretion of lymph but not plasma sphingosine-1-phosphate

Plasma sphingosine-1-phosphate (S1P) regulates vascular permeability, and plasma and lymph S1P guide lymphocyte egress from lymphoid organs. S1P is made intracellularly, and little is known about how S1P is delivered into circulatory fluids. Here we find that mice without the major facilitator super...

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Bibliographic Details
Main Authors: Mendoza, Alejandra, Bréart, Béatrice, Ramos-Perez, Willy D., Pitt, Lauren A., Gobert, Michael, Sunkara, Manjula, Lafaille, Juan J., Morris, Andrew J., Schwab, Susan R.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616498/
https://ncbi.nlm.nih.gov/pubmed/23103166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.09.021
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