Steroid Receptor Coactivator-interacting Protein (SIP) Inhibits Caspase-independent Apoptosis by Preventing Apoptosis-inducing Factor (AIF) from Being Released from Mitochondria

Apoptosis-inducing factor (AIF) is a caspase-independent death effector. Normally residing in the mitochondrial intermembrane space, AIF is released and translocated to the nucleus in response to proapoptotic stimuli. Nuclear AIF binds to DNA and induces chromatin condensation and DNA fragmentation,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wang, Dandan, Liang, Jing, Zhang, Yu, Gui, Bin, Wang, Feng, Yi, Xia, Sun, Luyang, Yao, Zhi, Shang, Yongfeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339961/
https://ncbi.nlm.nih.gov/pubmed/22371500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334151
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados