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Mechanism for Pre-B Cell Loss in V(H)-Mutant Rabbits
Pre-BCR signaling is a critical checkpoint in B cell development in which B-lineage cells expressing functional IgH μ-chain are selectively expanded. B cell development is delayed in mutant ali/ali rabbits because the a-allotype encoding V(H)1 gene, which is normally used in VDJ gene rearrangements...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3339493/ https://ncbi.nlm.nih.gov/pubmed/21957145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101778 |
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