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Accelerating Pd-Catalyzed C—F Bond Formation: Use of a Microflow Packed-Bed Reactor

[Image: see text] A flow process for Pd-catalyzed carbon fluorine bond formation is described. A microreactor using a packed-bed design allows for easy handling of large quantities of insoluble CsF with precise control over reaction times, efficient mixing, and the ability to safely handle elevated...

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Détails bibliographiques
Auteurs principaux: Noël, Timothy, Maimone, Thomas J., Buchwald, Stephen L.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339491/
https://ncbi.nlm.nih.gov/pubmed/21837710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201104652
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