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Cross-Regulations among NRFs and KEAP1 and Effects of their Silencing on Arsenic-Induced Antioxidant Response and Cytotoxicity in Human Keratinocytes
Background: Nuclear factor E2-related factors (NRFs), including NRF2 and NRF1, play critical roles in mediating the cellular adaptive response to oxidative stress. Human exposure to inorganic arsenic, a potent oxidative stressor, causes various dermal disorders, including hyperkeratosis and skin can...
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Główni autorzy: | , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
National Institute of Environmental Health Sciences
2012
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3339469/ https://ncbi.nlm.nih.gov/pubmed/22476201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1104580 |
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