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Thymoquinone decreases F-actin polymerization and the proliferation of human multiple myeloma cells by suppressing STAT3 phosphorylation and Bcl2/Bcl-(XL )expression
BACKGROUND: Thymoquinone (TQ), the major active component of the medicinal herb Nigella sativa Linn., has been described as a chemopreventive and chemotherapeutic compound. METHODS: In this study, we investigated the effect of TQ on survival, actin cytoskeletal reorganization, proliferation and sign...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3339355/ https://ncbi.nlm.nih.gov/pubmed/22177381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-10-236 |
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