Contribution of Cytochrome P450 1B1 to Hypertension and Associated Pathophysiology: A Novel Target for Antihypertensive Agents

The aim of this review is to discuss the contribution of cytochrome P450 (CYP) 1B1 in vascular smooth muscle cell growth, hypertension, and associated pathophysiology. CYP1B1 is expressed in cardiovascular and renal tissues, and mediates angiotensin II (Ang II)-induced activation of NADPH oxidase an...

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Bibliographic Details
Main Authors: Malik, Kafait U., Jennings, Brett L., Yaghini, Fariborz A., Sahan-Firat, Seyhan, Song, Chi Young, Estes, Anne M., Fang, Xiao R.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339277/
https://ncbi.nlm.nih.gov/pubmed/22210049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2011.12.003
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