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2,3′,4,5′-Tetramethoxystilbene prevents deoxycorticosterone-salt-induced hypertension: contribution of cytochrome P-450 1B1

Reactive oxygen species (ROS) contribute to various models of hypertension, including deoxycorticosterone acetate (DOCA)-salt-induced hypertension. Recently, we have shown that ROS, generated by cytochrome P-450 1B1 (CYP1B1) from arachidonic acid, mediate vascular smooth muscle cell growth caused by...

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Autors principals: Sahan-Firat, Seyhan, Jennings, Brett L., Yaghini, Fariborz A., Song, Chi Young, Estes, Anne M., Fang, Xiao R., Farjana, Nasreen, Khan, Amir I., Malik, Kafait U.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006285/
https://ncbi.nlm.nih.gov/pubmed/20852048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00655.2010
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