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Modulation of an ultraviolet mutational hotspot in a shuttle vector Xeroderma cells.

Ultraviolet mutagenesis of the shuttle vector plasmid pZ189 in Xeroderma Pigmentosum cells yields a mutational pattern marked by hotspots at photoproduct sites on both strands of the supF marker gene. In order to test the influence of strand orientation on the appearance of hotspots the mutagenesis...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Seetharam, S, Seidman, M M
Format: Artigo
Language:Inglês
Published: Oxford University Press 1991
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333921/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2027767/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.7.1601
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