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Modulation of an ultraviolet mutational hotspot in a shuttle vector Xeroderma cells.

Ultraviolet mutagenesis of the shuttle vector plasmid pZ189 in Xeroderma Pigmentosum cells yields a mutational pattern marked by hotspots at photoproduct sites on both strands of the supF marker gene. In order to test the influence of strand orientation on the appearance of hotspots the mutagenesis...

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Autors principals: Seetharam, S, Seidman, M M
Format: Artigo
Idioma:Inglês
Publicat: 1991
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC333921/
https://ncbi.nlm.nih.gov/pubmed/2027767
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