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The reaction of platinum(II) complexes with DNA. Kinetics of intrastrand crosslink formation in vitro.
The kinetics of the formation of bifunctional DNA platinum(II) adducts (DNA-crosslinks) have been investigated by endonuclease digestion and subsequent HPLC analysis of the soluble nucleotides and nucleotide platinum(II) adducts. The results indicate two waves of crosslinking [rate constants (0.2-0....
保存先:
| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
1991
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| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333905/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2027756/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.7.1483 |
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