Tolerability, pharmacokinetics and pharmacodynamics of CMAB007, a humanized anti-immunoglobulin E monoclonal antibody, in healthy Chinese subjects

The goal of the studies presented here was to determine the tolerability, pharmacokinetic and pharmacodynamic profiles of CMAB007, a biosimilar of omalizumab (Xolair; a humanized anti-immunoglobulin E monoclonal antibody), in healthy, male Chinese subjects. Thirty-six healthy Chinese men participate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Bo, Lin, Birong, Li, Jing, Qian, Weizhu, Hou, Sheng, Zhang, Dapeng, Kou, Geng, Li, Bohua, Wang, Hao, Chen, Yongchuan, Guo, Yajun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2012
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338945/
https://ncbi.nlm.nih.gov/pubmed/22327434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.4.1.18349
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