Tolerability, pharmacokinetics and pharmacodynamics of CMAB001, an anti-CD11a antibody, in Chinese healthy volunteers and psoriatic patients

AIM: To evaluate the pharmacokinetics (PK), pharmacodynamics (PD) and primary tolerability of an anti-CD11a monoclonal antibody (CMAB001) in Chinese healthy volunteers and psoriatic patients. METHODS: Two open-label studies were conducted. One was a parallel-group, single-center, dose-escalation tes...

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Detalhes bibliográficos
Main Authors: Li, Xian-ping, Li, Jing, Yan, Heng, Zhou, Bo, Li, Bo-hua, Qian, Wei-zhu, Hou, Sheng, Wang, Hao, Hao, Fei, Guo, Ya-jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011323/
https://ncbi.nlm.nih.gov/pubmed/22796761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.65
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