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Generation and characterization of human anti-human IL-21 neutralizing monoclonal antibodies
Interleukin 21 (IL-21) is a type I four-helical bundle cytokine that exerts a variety of significant effects on many hematopoietic cells, including T and B lymphocytes and natural killer cells. IL-21 is produced predominantly by CD4(+) T cells and natural killer T cells and, when aberrantly overexpr...
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主要な著者: | , , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Landes Bioscience
2012
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338942/ https://ncbi.nlm.nih.gov/pubmed/22327431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.4.1.18713 |
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