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Generation and characterization of human anti-human IL-21 neutralizing monoclonal antibodies

Interleukin 21 (IL-21) is a type I four-helical bundle cytokine that exerts a variety of significant effects on many hematopoietic cells, including T and B lymphocytes and natural killer cells. IL-21 is produced predominantly by CD4(+) T cells and natural killer T cells and, when aberrantly overexpr...

詳細記述

保存先:
書誌詳細
主要な著者: Maurer, Mark F, Garrigues, Ursula, Jaspers, Stephen R, Meengs, Brent, Rixon, Mark W, Stevens, Brenda L, Lewis, Kenneth B, Julien, Susan H, Bukowski, Thomas R, Wolf, Anitra C, Hamacher, Nels B, Snavely, Mark, Dillon, Stacey R
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338942/
https://ncbi.nlm.nih.gov/pubmed/22327431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.4.1.18713
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