Ceramide Kinase Regulates TNFα-Stimulated NADPH Oxidase Activity and Eicosanoid Biosynthesis in Neuroblastoma Cells

A persistent inflammatory reaction is a hallmark of chronic and acute pathologies in the central nervous system (CNS) and greatly exacerbates neuronal degeneration. The proinflammatory cytokine tumor necrosis factor alpha (TNFα) plays a pivotal role in the initiation and progression of inflammatory...

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Bibliographic Details
Main Authors: Barth, Brian M., Gustafson, Sally J., Hankins, Jody L., Kaiser, James M., Haakenson, Jeremy K., Kester, Mark, Kuhn, Thomas B.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338860/
https://ncbi.nlm.nih.gov/pubmed/22230689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.12.020
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