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Targeted Delivery of Chemotherapy Agents Using a Liver Cancer-Specific Aptamer
BACKGROUND: Using antibody/aptamer-drug conjugates can be a promising method for decreasing toxicity, while increasing the efficiency of chemotherapy. METHODOLOGY/PRINCIPAL FINDINGS: In this study, the antitumor agent Doxorubicin (Dox) was incorporated into the modified DNA aptamer TLS11a-GC, which...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338807/ https://ncbi.nlm.nih.gov/pubmed/22558072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033434 |
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