Promyelocytic Leukemia Zinc Finger Protein Activates GATA4 Transcription and Mediates Cardiac Hypertrophic Signaling from Angiotensin II Receptor 2

BACKGROUND: Pressure overload and prolonged angiotensin II (Ang II) infusion elicit cardiac hypertrophy in Ang II receptor 1 (AT(1)) null mouse, whereas Ang II receptor 2 (AT(2)) gene deletion abolishes the hypertrophic response. The roles and signals of the cardiac AT(2) receptor still remain unset...

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Main Authors: Wang, Ning, Frank, Gerald D., Ding, Ronghua, Tan, Zhongjia, Rachakonda, Amita, Pandolfi, Pier Paolo, Senbonmatsu, Takaaki, Landon, Erwin J., Inagami, Tadashi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338737/
https://ncbi.nlm.nih.gov/pubmed/22558183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035632
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