Antagonism or Synergism: Role of Tyrosine Phosphatases SHP-1 and SHP-2 in Growth Factor Signaling

SHP-1 and SHP-2 are two SH2 domain-containing tyrosine phosphatases with major pathological implications in cell growth regulating signaling. They share significant overall sequence identity, but their biological functions are often opposite. SHP-1 is generally considered as a negative signal transd...

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Библиографические подробности
Главные авторы: Wang, Ning, Li, Zhe, Ding, Ronghua, Frank, Gerald D., Senbonmatsu, Takaaki, Landon, Erwin J., Inagami, Tadashi, Zhao, Zhizhuang Joe
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377019/
https://ncbi.nlm.nih.gov/pubmed/16762922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M605018200
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