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Why Do Protein Folding Rates Correlate with Metrics of Native Topology?
For almost 15 years, the experimental correlation between protein folding rates and the contact order parameter has been under scrutiny. Here, we use a simple simulation model combined with a native-centric interaction potential to investigate the physical roots of this empirical observation. We sim...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338708/ https://ncbi.nlm.nih.gov/pubmed/22558173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035599 |
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