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Why Do Protein Folding Rates Correlate with Metrics of Native Topology?

For almost 15 years, the experimental correlation between protein folding rates and the contact order parameter has been under scrutiny. Here, we use a simple simulation model combined with a native-centric interaction potential to investigate the physical roots of this empirical observation. We sim...

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Bibliografski detalji
Glavni autori: Faísca, Patrícia F. N., Travasso, Rui D. M., Parisi, Andrea, Rey, Antonio
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338708/
https://ncbi.nlm.nih.gov/pubmed/22558173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035599
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